BDBM50135288 (1S,2R,3S,4R)-4-(6-Amino-purin-9-yl)-cyclopentane-1,2,3-triol::(1S,2R,3S,4R)-4-(6-amino-9H-purin-9-yl)cyclopentane-1,2,3-triol::CHEMBL129014::NORARISTEROMYCIN

SMILES c1nc(c2c(n1)n(cn2)[C@@H]3C[C@@H]([C@H]([C@H]3O)O)O)N

InChI Key InChIKey=VFKHECGAEJNAMV-UHFFFAOYSA-N

Data  4 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50135288   

TargetAdenosylhomocysteinase(Human)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288(CHEMBL129014 | (1S,2R,3S,4R)-4-(6-amino-9H-purin-9...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human SAHHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosylhomocysteinase(Plasmodium falciparum (isolate 3D7))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288(CHEMBL129014 | (1S,2R,3S,4R)-4-(6-amino-9H-purin-9...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Plasmodium falciparum SAHHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Plasmodium falciparum (isolate 3D7))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288(CHEMBL129014 | (1S,2R,3S,4R)-4-(6-amino-9H-purin-9...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory activity against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Human)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288(CHEMBL129014 | (1S,2R,3S,4R)-4-(6-amino-9H-purin-9...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against human S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosylhomocysteinase(Human)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288(CHEMBL129014 | (1S,2R,3S,4R)-4-(6-amino-9H-purin-9...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant SAHHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosylhomocysteinase(Human)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288(CHEMBL129014 | (1S,2R,3S,4R)-4-(6-amino-9H-purin-9...)
Affinity DataKi:  160nMAssay Description:Inhibitory activity against human S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosylhomocysteinase(Plasmodium falciparum (isolate 3D7))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288(CHEMBL129014 | (1S,2R,3S,4R)-4-(6-amino-9H-purin-9...)
Affinity DataKi:  180nMAssay Description:Inhibitory activity against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50135288(CHEMBL129014 | (1S,2R,3S,4R)-4-(6-amino-9H-purin-9...)
Affinity DataKi:  692nMAssay Description:Binding affinity to adenosine A2A receptor in rat striatal membranes by measuring displacement of specific [3H]-CGS- 21680 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50135288(CHEMBL129014 | (1S,2R,3S,4R)-4-(6-amino-9H-purin-9...)
Affinity DataKi:  3.30E+4nMAssay Description:Binding affinity to adenosine A1 receptor in rat brain membranes by measuring displacement of specific [3H]PIA as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed