BDBM7807 1-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-2,5-dione::Maleimide-Related Compound 6::N-Phenethyl-maleimide

SMILES O=C1C=CC(=O)N1CCc1ccccc1

InChI Key InChIKey=YDGBGLKCFQULNS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7807   

TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM7807(1-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-2,5-dione...)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Louvain Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM7807(1-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-2,5-dione...)
Affinity DataIC50: 7.61E+3nMAssay Description:Displacement of [3H]2-OG from human MGL by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Louvain Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM7807(1-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-2,5-dione...)
Affinity DataIC50: 2.49E+5nMAssay Description:Displacement of [3H]ethanolamine from human recombinant FAAH by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed