BDBM7418 (2 Z)-1-Methylindirubin::1-methyl-3-[(2Z)-3-oxo-2,3-dihydro-1H-indol-2-ylidene]-2,3-dihydro-1H-indol-2-one::N-methylindirubin::indirubin deriv. 12d

SMILES CN1C(=O)\C(=C2/Nc3ccccc3C2=O)c2ccccc12

InChI Key InChIKey=WDRLURVRNVIUKR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7418   

TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
University of Athens

LigandPNGBDBM7418(1-methyl-3-[(2Z)-3-oxo-2,3-dihydro-1H-indol-2-ylid...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Porcine)
University of Athens

LigandPNGBDBM7418(1-methyl-3-[(2Z)-3-oxo-2,3-dihydro-1H-indol-2-ylid...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
University of Athens

LigandPNGBDBM7418(1-methyl-3-[(2Z)-3-oxo-2,3-dihydro-1H-indol-2-ylid...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2006
Entry Details Article
PubMed