BDBM50429526 CHEMBL2333345::N-Hydroxycyclohexanecarboxamide

SMILES C1CCC(CC1)C(=O)NO

InChI Key InChIKey=RFWDAWXPYZTVSN-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50429526   

TargetHistone deacetylase 4(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429526(N-Hydroxycyclohexanecarboxamide | CHEMBL2333345)
Affinity DataIC50: 3.33E+4nMT: 2°CAssay Description:Inhibition of HDAC4 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429526(N-Hydroxycyclohexanecarboxamide | CHEMBL2333345)
Affinity DataIC50: 3.33E+4nMT: 2°CAssay Description:Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429526(N-Hydroxycyclohexanecarboxamide | CHEMBL2333345)
Affinity DataIC50: 3.72E+3nMT: 2°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429526(N-Hydroxycyclohexanecarboxamide | CHEMBL2333345)
Affinity DataIC50: 376nMT: 2°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed