BDBM50014875 (S)-7-Amino-1,2,3-trimethoxy-10-methylsulfanyl-6,7-dihydro-5H-benzo[a]heptalen-9-one::7-Amino-1,2,3-trimethoxy-10-methylsulfanyl-6,7-dihydro-5H-benzo[a]heptalen-9-one::CHEMBL298240::N-deacetylthiocolchicine::cid_426728

SMILES COc1cc2CC[C@H](N)c3cc(=O)c(SC)ccc3-c2c(OC)c1OC

InChI Key InChIKey=NUNCOHUMTCDISK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50014875   

TargetNuclear receptor subfamily 0 group B member 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50014875(CHEMBL298240 | cid_426728 | 7-Amino-1,2,3-trimetho...)
Affinity DataIC50: 212nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50014875(CHEMBL298240 | cid_426728 | 7-Amino-1,2,3-trimetho...)
Affinity DataIC50: 6.76E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetTubulin beta-2B chain(Bovine)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014875(CHEMBL298240 | cid_426728 | 7-Amino-1,2,3-trimetho...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory effect on the polymerization of purified bovine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014875(CHEMBL298240 | cid_426728 | 7-Amino-1,2,3-trimetho...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed