BDBM50370478 MORPHINE-6-GLUCURONIDE::Morphine 6-Glucuronide(Minor)::Morphine-6G

SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O)ccc5O

InChI Key InChIKey=GNJCUHZOSOYIEC-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50370478   

TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50370478(Morphine 6-Glucuronide(Minor) | MORPHINE-6-GLUCURO...)
Affinity DataEC50:  1.90E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Ultrafine Ufc

Curated by ChEMBL
LigandPNGBDBM50370478(Morphine 6-Glucuronide(Minor) | MORPHINE-6-GLUCURO...)
Affinity DataKi:  1.5nMAssay Description:mu-1 receptor binding affinity in rat brain by 3H [d-Ala2, d-Leu5] enkephalin displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50370478(Morphine 6-Glucuronide(Minor) | MORPHINE-6-GLUCURO...)
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]-DAMGO binding to recombinant human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Ultrafine Ufc

Curated by ChEMBL
LigandPNGBDBM50370478(Morphine 6-Glucuronide(Minor) | MORPHINE-6-GLUCURO...)
Affinity DataKi:  26nMAssay Description:mu-2 receptor binding affinity in rat brain by 3H [d-Ala2, (N-Me)Phe4, Gly5-ol] enkephalin displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50370478(Morphine 6-Glucuronide(Minor) | MORPHINE-6-GLUCURO...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]naloxone from MOR (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed