BDBM50107308 (E)-1-(2',4'-Dimethoxyphenyl)-3-(4''-methoxyphenyl)prop-2-en-1-one::(E)-1-(2,4-Dimethoxy-phenyl)-3-(4-methoxy-phenyl)-propenone::1-(2,4-Dimethoxy-phenyl)-3-(4-methoxy-phenyl)-propenone::CHEMBL36584::Metochalcone

SMILES COc1ccc(\C=C\C(=O)c2ccc(OC)cc2OC)cc1

InChI Key InChIKey=HVAKUYCEWDPRCA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50107308   

LigandPNGBDBM50107308(1-(2,4-Dimethoxy-phenyl)-3-(4-methoxy-phenyl)-prop...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of TNF-alpha-induced VCAM-1 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50107308(1-(2,4-Dimethoxy-phenyl)-3-(4-methoxy-phenyl)-prop...)
Affinity DataIC50: 2.34E+3nMAssay Description:Inhibition of BCRP in human MCF7/MX cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by FluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50107308(1-(2,4-Dimethoxy-phenyl)-3-(4-methoxy-phenyl)-prop...)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed