BDBM50428389 CHEMBL146816::Methyl 3-(4-Hydroxyphenyl)Acrylate::Methyl P-Hydroxycinnamate::Methyl Trans-P-Coumaric Acid::Methyl-P-Coumarate::P-Hydroxy Cinnamic Acid Methyl Ester

SMILES COC(=O)/C=C/c1ccc(cc1)O

InChI Key InChIKey=NITWSHWHQAQBAW-UHFFFAOYSA-N

Data  6 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50428389   

TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428389(Methyl 3-(4-Hydroxyphenyl)Acrylate | Methyl P-Hydr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human tyrosinase after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428389(Methyl 3-(4-Hydroxyphenyl)Acrylate | Methyl P-Hydr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human tyrosinase after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428389(Methyl 3-(4-Hydroxyphenyl)Acrylate | Methyl P-Hydr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of tyrosinase in neonatal human epidermal melanocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50428389(Methyl 3-(4-Hydroxyphenyl)Acrylate | Methyl P-Hydr...)
Affinity DataKi:  780nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50428389(Methyl 3-(4-Hydroxyphenyl)Acrylate | Methyl P-Hydr...)
Affinity DataKi:  800nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50428389(Methyl 3-(4-Hydroxyphenyl)Acrylate | Methyl P-Hydr...)
Affinity DataKi:  810nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50428389(Methyl 3-(4-Hydroxyphenyl)Acrylate | Methyl P-Hydr...)
Affinity DataKi:  820nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50428389(Methyl 3-(4-Hydroxyphenyl)Acrylate | Methyl P-Hydr...)
Affinity DataKi:  830nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50428389(Methyl 3-(4-Hydroxyphenyl)Acrylate | Methyl P-Hydr...)
Affinity DataKi:  850nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed