BDBM50305644 (2E,4E)-5-Benzo[1,3]dioxol-5-yl-penta-2,4-dienoic acid methyl ester::(2E,4E)-methyl 5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienoate::CHEMBL42965::Methyl piperate

SMILES COC(=O)\C=C\C=C\c1ccc2OCOc2c1

InChI Key InChIKey=VOZJBFJHMHRLDN-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50305644   

TargetAmine oxidase [flavin-containing] A(Rat)
General Hospital of Pla

Curated by ChEMBL
LigandPNGBDBM50305644((2E,4E)-methyl 5-(benzo[d][1,3]dioxol-5-yl)penta-2...)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
General Hospital of Pla

Curated by ChEMBL
LigandPNGBDBM50305644((2E,4E)-methyl 5-(benzo[d][1,3]dioxol-5-yl)penta-2...)
Affinity DataIC50: 230nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Mouse)
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50305644((2E,4E)-methyl 5-(benzo[d][1,3]dioxol-5-yl)penta-2...)
Affinity DataKi:  1.30E+3nMAssay Description:Competitive inhibition of mouse brain mitochondrial MAO-B using kynuramine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Mouse)
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50305644((2E,4E)-methyl 5-(benzo[d][1,3]dioxol-5-yl)penta-2...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of mouse brain MAOBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Mouse)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50305644((2E,4E)-methyl 5-(benzo[d][1,3]dioxol-5-yl)penta-2...)
Affinity DataKi:  2.71E+4nMAssay Description:Inhibition of mouse brain MAOAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed