BDBM50026777 2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol::2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol (methoxamine)::2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol(Methoxamine)::CHEMBL524::METHOXAMINE::Vasoxyl

SMILES COc1ccc(OC)c(c1)C(O)C(C)N

InChI Key InChIKey=WJAJPNHVVFWKKL-UHFFFAOYSA-N

Data  15 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50026777   

TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataIC50: 1.70E+5nMAssay Description:Binding affinity against alpha-1 adrenergic receptor is the ability to inhibit the specific [3H]prazosin binding (0.4 nM) to rat isolated brain membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataIC50: 3.60E+3nMAssay Description:50% inhibition of specific [3H]clonidine binding (0.4 nM) to Alpha-2 adrenergic receptors in rat isolated brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataEC50:  720nMAssay Description:Alpha-1 adrenergic receptor agonist activity in rabbit ear arteryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi:  940nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2011
Entry Details
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi:  1.61E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2011
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2011
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Hamster)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2011
Entry Details
PubMed
TargetSolute carrier family 22 member 1(Bovine)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2011
Entry Details
PubMed
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2011
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2011
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2011
Entry Details
PubMed
TargetAlpha-1B adrenergic receptor(Golden hamster)
National Children'S Medical Research Center

Curated by PDSP Ki Database
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2011
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
University of California

Curated by PDSP Ki Database
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
University of California

Curated by PDSP Ki Database
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2011
Entry Details
PubMed
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2011
Entry Details
PubMed
LigandPNGBDBM50026777(CHEMBL524 | Vasoxyl | 2-Amino-1-(2,5-dimethoxy-phe...)
Affinity DataKi:  1.10E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2011
Entry Details
PubMed