BDBM50423778 Leukerin::MERCAPTOPURINE::Mercaleukin::Mercaptopurine anhydrous::Purinethol

SMILES S=c1[nH]cnc2nc[nH]c12

InChI Key InChIKey=GLVAUDGFNGKCSF-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50423778   

TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Pontifical Catholic University of Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50423778(Mercaptopurine anhydrous | Leukerin | Mercaleukin ...)
Affinity DataKd:  7.94E+4nMAssay Description:Binding affinity to Mycobacterium tuberculosis purine nucleoside phosphorylase by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50423778(Mercaptopurine anhydrous | Leukerin | Mercaleukin ...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50423778(Mercaptopurine anhydrous | Leukerin | Mercaleukin ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human USP2 (258 to 605 residues) catalytic domain by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50423778(Mercaptopurine anhydrous | Leukerin | Mercaleukin ...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed