BDBM50312636 (-)-Makaluvamine F::CHEMBL509890::Makaluvamine F

SMILES Oc1cc2SC(Cc2cc1Br)NC1=CC2=NCCc3c[nH]c(c23)C1=O

InChI Key InChIKey=ZEIRCDSUNJVVPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312636   

TargetSortase family protein(Staphylococcus aureus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50312636(Makaluvamine F | (-)-Makaluvamine F | CHEMBL509890)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of Staphylococcus aureus sortase A after 1 hr in the presence of fluorescent peptide Dabcul-QALPETGEE-Edans by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50312636(Makaluvamine F | (-)-Makaluvamine F | CHEMBL509890)
Affinity DataIC50: 8.30E+3nMAssay Description:Displacement of GST-tagged p300-CH1 domain (323 to 423 residues) from synthetic biotinylated HIF-1alpha C-TAD domain (786 to 826 residues) (unknown o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2018
Entry Details Article
PubMed