BDBM23619 2-{4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl}-N-(2,6-dimethylphenyl)acetamide::CHEMBL92870::Clinium::Corflazine::Lidoflazine::Ordiflazine

SMILES Cc1cccc(C)c1NC(=O)CN1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1

InChI Key InChIKey=ZBIAKUMOEKILTF-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 23619   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM23619(CHEMBL92870 | Clinium | Corflazine | 2-{4-[4,4-bis...)
Affinity DataIC50: 15.8nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM23619(CHEMBL92870 | Clinium | Corflazine | 2-{4-[4,4-bis...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of veratridine-induced Na+ influx in chinese hamster ovary cells expressing alpha subunit of rat brain type voltage-gated sodium channel t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM23619(CHEMBL92870 | Clinium | Corflazine | 2-{4-[4,4-bis...)
Affinity DataIC50: 15.8nMAssay Description:Inhibitory concentration against potassium channel HERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandPNGBDBM23619(CHEMBL92870 | Clinium | Corflazine | 2-{4-[4,4-bis...)
Affinity DataKi:  188nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Science Center

LigandPNGBDBM23619(CHEMBL92870 | Clinium | Corflazine | 2-{4-[4,4-bis...)
Affinity DataKi:  280nM ΔG°:  -8.84kcal/mole IC50: 4.95E+3nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
LigandPNGBDBM23619(CHEMBL92870 | Clinium | Corflazine | 2-{4-[4,4-bis...)
Affinity DataKi:  305nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed