BDBM50423773 A-1544750::CEP-701::KT-5555::LESTAURTINIB::SP924

SMILES C[C@]12O[C@@H](C[C@@]1(O)CO)n1c3ccccc3c3c4C(=O)NCc4c4c5ccccc5n2c4c13

InChI Key InChIKey=UIARLYUEJFELEN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50423773   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423773(A-1544750 | CEP-701 | KT-5555 | SP924 | LESTAURTIN...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human FMS expressed in growth factor dependent mouse FDC-P1 cells assessed as inhibition of FMS-mediated cell proliferation in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50423773(A-1544750 | CEP-701 | KT-5555 | SP924 | LESTAURTIN...)
Affinity DataIC50: 5nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50423773(A-1544750 | CEP-701 | KT-5555 | SP924 | LESTAURTIN...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of recombinant FLT3 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed