BDBM36334 CID644294::JPM 565::JPM-OEt::US9345789, JPM-Oet

SMILES [H][C@](NC(=O)[C@@]1([H])O[C@]1([H])C(=O)OCC)(C(C)CC)C(=O)NCCc1ccc(O)cc1

InChI Key InChIKey=RZHVVXDUYUESJI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 36334   

TargetCathepsin B(Mouse)
Stanford University

LigandPNGBDBM36334(JPM 565 | CID644294 | JPM-OEt | US9345789, JPM-Oet)
Affinity DataIC50: 780nMpH: 6.25 T: 2°CAssay Description:IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2011
Entry Details Article
PubMed
TargetProcathepsin L(Mouse)
Stanford University

LigandPNGBDBM36334(JPM 565 | CID644294 | JPM-OEt | US9345789, JPM-Oet)
Affinity DataIC50: 2.98E+3nMpH: 6.25 T: 2°CAssay Description:IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2011
Entry Details Article
PubMed
TargetCathepsin B(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM36334(JPM 565 | CID644294 | JPM-OEt | US9345789, JPM-Oet)
Affinity DataIC50: 780nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent

TargetProcathepsin L(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM36334(JPM 565 | CID644294 | JPM-OEt | US9345789, JPM-Oet)
Affinity DataIC50: 2.98E+3nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent