BDBM50216157 11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione::3,11-dihydro-2,5,11,11b-tetraaza-benzo[a]trindene-4,6-dione::CHEMBL413188::isogranulatimide

SMILES O=C1NC(=O)c2c1c1cncn1c1[nH]c3ccccc3c21

InChI Key InChIKey=WXUJAQBSBZLVEV-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50216157   

TargetSerine/threonine-protein kinase Chk1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cdk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human Chk1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Chk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50: 500nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed