BDBM10625 ({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-ylamino)phosphoryl)(propan-2-yl)amine::CHEMBL494887::iso-OMPA::tetra(monoisopropyl)pyrophosphortetramide

SMILES CC(C)NP(=O)(NC(C)C)OP(=O)(NC(C)C)NC(C)C

InChI Key InChIKey=IOIMDJXKIMCMIG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 10625   

TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50: 3.40E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50: 980nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50: 134nMpH: 8.0Assay Description:The reaction mixture was consisted of 100 µL of the total volume. To the solution of PBS (pH 8.0, 30 µL) consisted of KH2PO4 and K2HPO4 in 96-well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50: 733nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed