BDBM50182880 CHEMBL147741::indole-3-carboxaldehyde

SMILES c1ccc2c(c1)c(c[nH]2)C=O

InChI Key InChIKey=OLNJUISKUQQNIM-UHFFFAOYSA-N

Data  1 KI  4 IC50

PDB links: 5 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50182880   

TargetCytochrome P450 2A6(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50182880(indole-3-carboxaldehyde | CHEMBL147741)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin 7 as substrate preincubated for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182880(indole-3-carboxaldehyde | CHEMBL147741)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPteridine reductase 1(Leishmania major)
Rutgers University

Curated by ChEMBL
LigandPNGBDBM50182880(indole-3-carboxaldehyde | CHEMBL147741)
Affinity DataIC50: 1.10E+6nMAssay Description:Inhibition of Leishmania major PTR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Leishmania major)
Rutgers University

Curated by ChEMBL
LigandPNGBDBM50182880(indole-3-carboxaldehyde | CHEMBL147741)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of Leishmania major DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50182880(indole-3-carboxaldehyde | CHEMBL147741)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin 7 as substrate preincubated for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed