BDBM50199518 (-)-huperzine B::CHEMBL245079::huperzine B

SMILES CC1=C[C@H]2Cc3[nH]c(=O)ccc3[C@]3(C1)NCCC[C@H]23

InChI Key

Data  2 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50199518   

TargetAcetylcholinesterase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50199518(huperzine B | (-)-huperzine B | CHEMBL245079)
Affinity DataIC50: 1.93E+4nMpH: 5.0Assay Description:Inhibition of AChE in rat cortex at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50199518(huperzine B | (-)-huperzine B | CHEMBL245079)
Affinity DataIC50: 2.28E+5nMAssay Description:Inhibition of BuChE in rat serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50199518(huperzine B | (-)-huperzine B | CHEMBL245079)
Affinity DataEC50:  19nMAssay Description:In vitro reversal of vecuronium-induced neuromuscular block in guinea pig hemi-diaphragm.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50199518(huperzine B | (-)-huperzine B | CHEMBL245079)
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of human recombinant AChE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50199518(huperzine B | (-)-huperzine B | CHEMBL245079)
Affinity DataKi:  334nMAssay Description:Inhibition of Torpedo californica AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50199518(huperzine B | (-)-huperzine B | CHEMBL245079)
Affinity DataKi:  794nMAssay Description:Inhibitory constant against fetal bovine serum (FBS) acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed