BDBM50422274 GONADORELIN::Human gonadoliberin-i

SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O

InChI Key InChIKey=XLXSAKCOAKORKW-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50422274   

TargetGonadotropin-releasing hormone receptor(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50422274(Human gonadoliberin-i | GONADORELIN)
Affinity DataIC50: 7nMAssay Description:The compound was tested for the concentration to inhibit 50% of [125 I]leuprorelin binding to Leutinizing releasing hormone receptor in the membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50422274(Human gonadoliberin-i | GONADORELIN)
Affinity DataIC50: 6nMAssay Description:The compound was tested for the concentration to inhibit 50% of [125 I]leuprorelin binding to Leutinizing releasing hormone receptor the membrane fra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50422274(Human gonadoliberin-i | GONADORELIN)
Affinity DataIC50: 10nMAssay Description:The Compound was tested for the concentration to inhibit 50% of [125 I ]leuprorelin binding to the cloned human Leutinizing releasing hormone recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50422274(Human gonadoliberin-i | GONADORELIN)
Affinity DataIC50: 2nMAssay Description:Concentration of the peptide which displaces 50% of 125 I-[D-Lys6] gonadotropin-releasing hormone bound to rat pituitary membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50422274(Human gonadoliberin-i | GONADORELIN)
Affinity DataKi:  1.30nMAssay Description:In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed