BDBM18122 (4S)-4-amino-5-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-5-oxopentanoic acid::5-O-[N-(L-Glutamyl)-sulfamoyl]adenosine 5::Glu-AMS

SMILES N[C@@H](CCC(O)=O)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=YBRKRYFZKHICLS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18122   

TargetGlutamate--tRNA ligase(Escherichia coli (strain K12))
Crefsip

LigandPNGBDBM18122(5-O-[N-(L-Glutamyl)-sulfamoyl]adenosine 5 | (4S)-4...)
Affinity DataKi:  2.80nM ΔG°:  -12.1kcal/molepH: 7.2 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2007
Entry Details Article
PubMed
LigandPNGBDBM18122(5-O-[N-(L-Glutamyl)-sulfamoyl]adenosine 5 | (4S)-4...)
Affinity DataKi:  70nM ΔG°:  -9.92kcal/molepH: 8.0 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2007
Entry Details Article
PubMed