BDBM50073119 CHEMBL107747::Gemopatrilat::[(S)-6-((S)-2-Mercapto-3-phenyl-propionylamino)-2,2-dimethyl-7-oxo-azepan-1-yl]-acetic acid

SMILES CC1(C)CCC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C(=O)N1CC(O)=O

InChI Key InChIKey=YRSVDSQRGBYVIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50073119   

TargetAngiotensin-converting enzyme(Rabbit)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073119(Gemopatrilat | [(S)-6-((S)-2-Mercapto-3-phenyl-pro...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzyme (ACE) isolated from rabbit lung extract using hippuryl-L-histidyl-L-leucine (HHL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Rat)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073119(Gemopatrilat | [(S)-6-((S)-2-Mercapto-3-phenyl-pro...)
Affinity DataIC50: 63nMAssay Description:In vitro inhibitory activity against purified rat kidney neutral endopeptidase (NEP) using a fluorometric assay with dansyl-Gly-Phe-Arg as the substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed