BDBM50423644 GALACTOSE

SMILES C([C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O

InChI Key InChIKey=WQZGKKKJIJFFOK-UHFFFAOYSA-N

Data  2 IC50  4 Kd

PDB links: 287 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50423644   

TargetGalectin-1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50423644(GALACTOSE)
Affinity DataIC50: 5.00E+7nMAssay Description:Inhibition of recombinant galectin 1 in human O type red blood cells by hemagglutinination assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGalectin-3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50423644(GALACTOSE)
Affinity DataIC50: 5.00E+7nMAssay Description:Inhibition of recombinant galectin 3 in human O type red blood cells by hemagglutinination assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetPA-I galactophilic lectin(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50423644(GALACTOSE)
Affinity DataKd:  8.75E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa PAO1 LecA assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPA-I galactophilic lectin(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50423644(GALACTOSE)
Affinity DataKd:  8.80E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa LecA assessed as change in enthalpyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPA-I galactophilic lectin(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50423644(GALACTOSE)
Affinity DataKd:  8.80E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa LecA assessed as change in entropyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPA-I galactophilic lectin(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50423644(GALACTOSE)
Affinity DataKd:  8.80E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa LecA assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)