BDBM50040241 3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine(fluperlapine)::CHEMBL63756::Fluperlapine

SMILES CN1CCN(CC1)C1=Nc2cc(F)ccc2Cc2ccccc12

InChI Key InChIKey=OBWGMKKHCLHVIE-UHFFFAOYSA-N

Data  30 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50040241   

TargetSerotonin 2 (5-HT2) receptor(Rat)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  3.80nMAssay Description:In vitro binding affinity against rat 5-hydroxytryptamine 2 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  4.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  7.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  7.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  8.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  16.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  18.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  18.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  19.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  21nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  25nMAssay Description:In vitro binding affinity against Muscarinic acetylcholine receptors in rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Washington

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  29nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  41nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Albany Medical College

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  56nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  71nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  75nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Mouse)
Novo Industri

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  85nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  132nMAssay Description:Binding affinity against dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  133nMAssay Description:In vitro binding affinity against Dopamine D2 receptor in rat striatal tissue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  141nMAssay Description:In vitro binding affinity against Dopamine receptor D1 in rat striatal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  141nMAssay Description:Binding affinity against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Novo Industri

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  245nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  255nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2012
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
University of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  316nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  316nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetD(1B) dopamine receptor(Rat)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM50040241(CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  510nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details Article
PubMed