BDBM50340677 (5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione::5 fluorouracil::5-FU::5-Florouracil::5-Fluoro-1H-pyrimidine-2,4-dione::5-Fluoro-1H-pyrimidine-2,4-dione (5-FU)::5-Fluoro-1H-pyrimidine-2,4-dione (5-Fluorouracil)::5-Fluoro-1H-pyrimidine-2,4-dione(5-FU)::5-Fluoro-1H-pyrimidine-2,4-dione(5-FUra)::5-Fluoro-1H-pyrimidine-2,4-dione(5-fluoro uracil)::5-Fluoro-1H-pyrimidine-2,4-dione(5-fluorouracil)(5-FU)::5-Fluoro-1H-pyrimidine-2,4-dione(5FU)::5-Fluorouracil::5-fluoro-uracil::5-fluoropyrimidine-2,4(1H,3H)-dione::5-fluorouacil::5-fluorourasil::5F-uracil::Adrucil::CHEMBL185::Carac::Efudex::FLUOROURACIL, 5-::Fluoroplex::Fluracil::Ro-2-9757
SMILES C1=C(C(=O)NC(=O)N1)F
InChI Key InChIKey=GHASVSINZRGABV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50340677
Affinity DataIC50: 320nMpH: 7.4 T: 2°CAssay Description:Compounds 1-32 were dissolved in 100% DMSO and diluted to the appropriate concentrations with 25 mM HEPES at pH 7.4. In each well, 10 μL of comp...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of human recombinant aromatase expressed in baculovirus insect cell using 7-methoxy-trifluoromethyl coumarin (MFC) as substrate preincubat...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of Escherichia coli K-12 MTCC 1302 UPRT activity by spectrophotometryMore data for this Ligand-Target Pair