BDBM3973 N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide::cid_58035::erbstatin

SMILES Oc1ccc(O)c(\C=C\NC=O)c1

InChI Key InChIKey=SIHZWGODIRRSRA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 3973   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3973(N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide | ...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3973(N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide | ...)
Affinity DataIC50: 1.40E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2005
Entry Details Article
PubMed
TargetM18 aspartyl aminopeptidase(Plasmodium falciparum (isolate 3D7))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM3973(N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide | ...)
Affinity DataIC50: 3.72E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetProcathepsin L(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM3973(N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide | ...)
Affinity DataIC50: 5.96E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3973(N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide | ...)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3973(N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide | ...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3973(N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide | ...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
LigandPNGBDBM3973(N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide | ...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed