BDBM50236240 5alpha-androstan-3beta-OL-17-one::CHEMBL272195::Epiandrosterone::epi-andosterone

SMILES C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O

InChI Key InChIKey=QGXBDMJGAMFCBF-UHFFFAOYSA-N

Data  4 KI  2 IC50  1 EC50

PDB links: 5 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50236240   

TargetG-protein coupled bile acid receptor 1(Human)
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50236240(Epiandrosterone | epi-andosterone | 5alpha-androst...)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at human TGR5 expressed in CHO cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50236240(Epiandrosterone | epi-andosterone | 5alpha-androst...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50236240(Epiandrosterone | epi-andosterone | 5alpha-androst...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of G6PD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Trypanosoma brucei)
Universidade De SãO Paulo

Curated by ChEMBL
LigandPNGBDBM50236240(Epiandrosterone | epi-andosterone | 5alpha-androst...)
Affinity DataKi:  460nMAssay Description:Inhibition of Trypanosoma brucei G6PDH using NADP as substrate by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Trypanosoma brucei)
Universidade De SãO Paulo

Curated by ChEMBL
LigandPNGBDBM50236240(Epiandrosterone | epi-andosterone | 5alpha-androst...)
Affinity DataKi:  490nMAssay Description:Inhibition of Trypanosoma brucei G6PDH using glucose-6-phosphate as substrate by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50236240(Epiandrosterone | epi-andosterone | 5alpha-androst...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human G6PDH using NADP as substrate by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50236240(Epiandrosterone | epi-andosterone | 5alpha-androst...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of human G6PDH using glucose-6-phosphate as substrate by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed