BDBM50020174 1-Benzofuran-7-yl-4-[5-(4-fluoro-phenyl)-1H-pyrrol-2-ylmethyl]-piperazine::CHEMBL292187::Elopiprazole

SMILES Fc1ccc(cc1)-c1ccc(CN2CCN(CC2)c2cccc3ccoc23)[nH]1

InChI Key InChIKey=PGNHBJGIQAEIHD-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50020174   

TargetD(2) dopamine receptor(Human)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50020174(CHEMBL292187 | 1-Benzofuran-7-yl-4-[5-(4-fluoro-ph...)
Affinity DataKi:  0.420nMAssay Description:Binding affinity for dopamine receptor D2 determined using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020174(CHEMBL292187 | 1-Benzofuran-7-yl-4-[5-(4-fluoro-ph...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]-Spiperone from Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50020174(CHEMBL292187 | 1-Benzofuran-7-yl-4-[5-(4-fluoro-ph...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020174(CHEMBL292187 | 1-Benzofuran-7-yl-4-[5-(4-fluoro-ph...)
Affinity DataKi:  120nMAssay Description:Potency to displace [3H]- Spiperone from 5-hydroxytryptamine 2 receptor in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020174(CHEMBL292187 | 1-Benzofuran-7-yl-4-[5-(4-fluoro-ph...)
Affinity DataKi:  220nMAssay Description:Potency to displace [3H]- WB-4101 from alpha-1 adrenergic receptor in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed