BDBM50282617 6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-4,5-dihydropyridazin-3(2H)-one::CHEMBL24646::US20240308973, Example Pimobendan::dl-Pimobendan::pimobendan

SMILES COc1ccc(cc1)-c1nc2ccc(cc2[nH]1)C1=NNC(=O)CC1C

InChI Key InChIKey=GLBJJMFZWDBELO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50282617   

TargetType-1 angiotensin II receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50282617(6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-met...)
Affinity DataIC50: 1.70E+4nMAssay Description:Concentration required for 50% inhibition of binding against Angiotensin II receptor, type 1 in bovine adrenal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM50282617(6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-met...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of phosphodiesterase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article

LigandPNGBDBM50282617(6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-met...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of phosphodiesterase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article

TargetPhosphodiesterase(Dog)
Zoetis Services

US Patent
LigandPNGBDBM50282617(6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-met...)
Affinity DataIC50: 1.53E+3nMAssay Description:The canine PDE3A assay kit was purchased from BPS Bioscience (San Diego, CA) which included dog PDE3A recombinant enzyme, FAM-cyclic-3',5'-AMP (20 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent