BDBM82016 CAS_479-18-5::DYPHYLLINE::Dihydroxypropyltheophylline::Diprophylline::Dylin::Dylix::Lufyllin::NSC_3182::Neothylline

SMILES CN1c2c(n(cn2)C[C@@H](CO)O)C(=O)N(C1=O)C

InChI Key InChIKey=KSCFJBIXMNOVSH-UHFFFAOYSA-N

Data  3 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 82016   

TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM82016(Diprophylline | NSC_3182 | CAS_479-18-5 | DYPHYLLI...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM82016(Diprophylline | NSC_3182 | CAS_479-18-5 | DYPHYLLI...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM82016(Diprophylline | NSC_3182 | CAS_479-18-5 | DYPHYLLI...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM82016(Diprophylline | NSC_3182 | CAS_479-18-5 | DYPHYLLI...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details Article
PubMed