BDBM66977 3-[(3S,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3,14-bis(oxidanyl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one::3-[(3S,5R,8R,9S,10S,13R,14S,17R)-3,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one::Digitoxigenin::MLS002153810::SMR001233182::cid_4369270

SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@]34C)[C@@]1(O)CC[C@@H]2C1=CC(=O)OC1

InChI Key InChIKey=XZTUSOXSLKTKJQ-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 66977   

TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66977(Digitoxigenin | cid_4369270 | MLS002153810 | 3-[(3...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium-transporting ATPase alpha chain 2(Human)
Prassis Istituto Di Ricerche Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM66977(Digitoxigenin | cid_4369270 | MLS002153810 | 3-[(3...)
Affinity DataIC50: 80nMAssay Description:Compound was evaluated for its ability to inhibit the specific [3H]-ouabain binding to dog kidney Na+/K+ ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
Prassis Istituto Di Ricerche Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM66977(Digitoxigenin | cid_4369270 | MLS002153810 | 3-[(3...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Na+/K+ ATPase from dog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
Prassis Istituto Di Ricerche Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM66977(Digitoxigenin | cid_4369270 | MLS002153810 | 3-[(3...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory concentration against dog kidney Na+,K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed