BDBM50276568 CHEMBL1685::DEZOCINE::Dalgan::US10231963, Table B.7::US9656961, Example 00124::WY-16225

SMILES C[C@@]12CCCCC[C@@H](Cc3ccc(O)cc13)[C@@H]2N

InChI Key InChIKey=VTMVHDZWSFQSQP-UHFFFAOYSA-N

Data  2 KI  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50276568   

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276568(CHEMBL1685 | Dalgan | WY-16225 | DEZOCINE | US9656...)
Affinity DataEC50:  38nMAssay Description:Activity at human cloned mu opioid receptor assessed as reversal of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276568(CHEMBL1685 | Dalgan | WY-16225 | DEZOCINE | US9656...)
Affinity DataEC50:  20nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276568(CHEMBL1685 | Dalgan | WY-16225 | DEZOCINE | US9656...)
Affinity DataIC50: 130nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276568(CHEMBL1685 | Dalgan | WY-16225 | DEZOCINE | US9656...)
Affinity DataEC50:  20nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276568(CHEMBL1685 | Dalgan | WY-16225 | DEZOCINE | US9656...)
Affinity DataIC50: 130nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276568(CHEMBL1685 | Dalgan | WY-16225 | DEZOCINE | US9656...)
Affinity DataKi:  0.540nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276568(CHEMBL1685 | Dalgan | WY-16225 | DEZOCINE | US9656...)
Affinity DataKi:  0.540nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent