BDBM50217055 CHEMBL1835612::CHEMBL231592::N-(2-[6-bromo-2(1,1-dimethyl-2-propenyl)-1H-indol-3-yl]ethyl)-N-methylamine::desformylflustrabromine

SMILES CNCCc1c([nH]c2cc(Br)ccc12)C(C)(C)C=C

InChI Key InChIKey=GQHSCJUTJKLZPX-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50217055   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50217055(CHEMBL1835612 | N-(2-[6-bromo-2(1,1-dimethyl-2-pro...)
Affinity DataIC50: 4.40E+4nMAssay Description:Activity at human alpha7 nACh receptor expressed in Xenopus oocytes assessed as inhibition of acetyl chlone-induced currents by two-electrode voltage...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50217055(CHEMBL1835612 | N-(2-[6-bromo-2(1,1-dimethyl-2-pro...)
Affinity DataIC50: 1.50E+5nMAssay Description:Activity at human alpha-4-beta-2 nACh receptor expressed in Xenopus oocytes assessed as inhibition of acetyl chlone-induced currents by two-electrode...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50217055(CHEMBL1835612 | N-(2-[6-bromo-2(1,1-dimethyl-2-pro...)
Affinity DataEC50:  320nMAssay Description:Agonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as potentiation of acetylcholine-induced current by two electrode vo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50217055(CHEMBL1835612 | N-(2-[6-bromo-2(1,1-dimethyl-2-pro...)
Affinity DataEC50:  331nMAssay Description:Agonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as potentiation of acetylcholine-induced current by two electrode vo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50217055(CHEMBL1835612 | N-(2-[6-bromo-2(1,1-dimethyl-2-pro...)
Affinity DataEC50:  1.86E+3nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed