BDBM50131047 14-Methyl-5-oxo-5,7,8,13-tetrahydro-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-14-ium::CHEMBL81923::dehydroevidiamine::dehydroevodiamine::dehydroevodiamine chloride::dehydroevodiamine hydrochloride

SMILES C[n+]1c2-c3[nH]c4ccccc4c3CCn2c(=O)c2ccccc12

InChI Key InChIKey=VXHNSVKJHXSKKM-UHFFFAOYSA-O

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50131047   

TargetCytochrome P450 1A2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131047(dehydroevodiamine chloride | 14-Methyl-5-oxo-5,7,8...)
Affinity DataIC50: 5.63E+3nMAssay Description:Inhibition of Cytochrome P450 1A2 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131047(dehydroevodiamine chloride | 14-Methyl-5-oxo-5,7,8...)
Affinity DataIC50: 1.81E+4nMAssay Description:Inhibition of Cytochrome P450 1A1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131047(dehydroevodiamine chloride | 14-Methyl-5-oxo-5,7,8...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human Cytochrome P450 1B1 expressed in bacterial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Research Instituter of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131047(dehydroevodiamine chloride | 14-Methyl-5-oxo-5,7,8...)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of [3H]prazosin from alpha1 adrenoceptor in rat heart membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed