BDBM50002805 (daltroban){4-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-phenyl}-acetic acid::BM 13505::BM-13505::CHEMBL71685::Daltroban::{4-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-phenyl}-acetic acid

SMILES c1cc(ccc1CCNS(=O)(=O)c2ccc(cc2)Cl)CC(=O)O

InChI Key InChIKey=IULOBWFWYDMECP-UHFFFAOYSA-N

Data  3 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50002805   

TargetThromboxane A2 receptor(Human)
Pharmacia-Farmitalia Carlo Erba

Curated by ChEMBL
LigandPNGBDBM50002805(CHEMBL71685 | (daltroban){4-[2-(4-Chloro-benzenesu...)
Affinity DataIC50: 150nMAssay Description:In vitro thromboxane-A2 receptor binding affinity to displace by 50% [3H]-SQ 29548 binding from washed human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Pharmacia-Farmitalia Carlo Erba

Curated by ChEMBL
LigandPNGBDBM50002805(CHEMBL71685 | (daltroban){4-[2-(4-Chloro-benzenesu...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of thromboxane-A2 synthase in rat whole blood during clotting at 37 degrees CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Rat)
Zeria Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002805(CHEMBL71685 | (daltroban){4-[2-(4-Chloro-benzenesu...)
Affinity DataIC50: 37nMAssay Description:In vitro thromboxane A2 antagonistic activity on U-46619 (0.1 uM) induced contraction of rat aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Pharmacia-Farmitalia Carlo Erba

Curated by ChEMBL
LigandPNGBDBM50002805(CHEMBL71685 | (daltroban){4-[2-(4-Chloro-benzenesu...)
Affinity DataIC50: 460nMAssay Description:In vitro thromboxane A2 antagonistic activity on aggregation of rabbit platelets induced by U-46,619 (4 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Pharmacia-Farmitalia Carlo Erba

Curated by ChEMBL
LigandPNGBDBM50002805(CHEMBL71685 | (daltroban){4-[2-(4-Chloro-benzenesu...)
Affinity DataKi:  5.43nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetThromboxane A2 receptor(Human)
Pharmacia-Farmitalia Carlo Erba

Curated by ChEMBL
LigandPNGBDBM50002805(CHEMBL71685 | (daltroban){4-[2-(4-Chloro-benzenesu...)
Affinity DataKi:  11.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetThromboxane A2 receptor(Human)
Pharmacia-Farmitalia Carlo Erba

Curated by ChEMBL
LigandPNGBDBM50002805(CHEMBL71685 | (daltroban){4-[2-(4-Chloro-benzenesu...)
Affinity DataKi:  63nMAssay Description:Compound was tested for its binding affinity at Thromboxane A2/ Prostaglandin H2 receptor by measuring its ability to displace [3H]U-46619 from guine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed