BDBM50308520 CHEMBL603622::cyclophostin

SMILES CO[P@]1(=O)OC[C@H]2COC(=O)C2=C(C)O1

InChI Key InChIKey=OMPQJMDGDAAXPE-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50308520   

TargetHormone-sensitive lipase(Rat)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(cyclophostin | CHEMBL603622)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(cyclophostin | CHEMBL603622)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(cyclophostin | CHEMBL603622)
Affinity DataIC50: 40nMAssay Description:Inhibition of human AChE at pH 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(House fly)
University of Missouri-St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(cyclophostin | CHEMBL603622)
Affinity DataIC50: 0.760nMAssay Description:Inhibition of housefly CSMA AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(cyclophostin | CHEMBL603622)
Affinity DataIC50: 45nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(cyclophostin | CHEMBL603622)
Affinity DataKi:  140nMAssay Description:Irreversible inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed