BDBM50241503 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-1-Benzopyrylium::2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromenylium::3,3',4',5,7-pentahydroxyflavylium::3,5,7,3'',4''-Pentahydroxyflavylium::CHEMBL404515::CHEMBL511367::Cyanidin::cyanidin(1+)

SMILES Oc1cc2oc(c(O)cc2c(=[OH+])c1)-c1ccc(O)c(O)c1

InChI Key InChIKey=QFCUROSHGOWZEG-UHFFFAOYSA-O

Data  9 IC50  3 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50241503   

TargetOxysterols receptor LXR-beta(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataEC50:  1.25E+5nMAssay Description:Agonist activity at human LXRbeta-LBD assessed as recruitment of co-activator peptide after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human LXRalpha-LBD assessed as recruitment of co-activator peptide after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataKd:  7.32E+4nMAssay Description:Binding affinity to human LXRbeta-LBD by surface plasmon resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to human LXRalpha-LBD by surface plasmon resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Lodz

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataKd:  7.80nMAssay Description:Inhibition of human thrombin assessed as equilibrium dissociation constant at 50 to 1000 uM by BIAcore analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Lodz

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human thrombin amidolytic activity using D-Phe-Pip-Arg-pNA as substrate preincubated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Department of Horticulture and National Food Safety and Toxicology Center

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataIC50: 6.00E+7nMAssay Description:Inhibition of PGHS2 assessed as conversion of arachidonic acid to prostaglandinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Department of Horticulture and National Food Safety and Toxicology Center

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataIC50: 9.00E+7nMAssay Description:Inhibition of PGHS1 assessed as conversion of arachidonic acid to prostaglandinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataIC50: 1.50E+5nMAssay Description:Displacement of ANS from DAPK1 catalytic domain (1 to 285) (unknown origin) after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Tokyo University of Science

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human recombinant glyoxalase 1 assessed as S-D-lactoylglutathione after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of human CD38 using 20 uM 1, N6-etheno NAD+ as substrate by continuous fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Department of Horticulture and National Food Safety and Toxicology Center

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataIC50: 6.00E+7nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Department of Horticulture and National Food Safety and Toxicology Center

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataIC50: 9.00E+7nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetAlpha-glucosidase MAL62(Baker's yeast)TBA
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of baker's yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article