BDBM13373 (2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-methylbutanamido]-3-phenylpropanamido]-4-(methylsulfanyl)butanoic acid::CHEMBL289302::CHEMBL553980::CVFM

SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O

InChI Key InChIKey=PCFMKLVXKKAJSV-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 13373   

LigandPNGBDBM13373(CHEMBL289302 | CHEMBL553980 | (2S)-2-[(2S)-2-[(2S)...)
Affinity DataIC50: 600nMpH: 7.5 T: 2°CAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Centre De Recherches De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM13373(CHEMBL289302 | CHEMBL553980 | (2S)-2-[(2S)-2-[(2S)...)
Affinity DataIC50: 37nMAssay Description:Inhibition of [3H]FPP incorporation into human Ha-Ras by farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM13373(CHEMBL289302 | CHEMBL553980 | (2S)-2-[(2S)-2-[(2S)...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of Human farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM13373(CHEMBL289302 | CHEMBL553980 | (2S)-2-[(2S)-2-[(2S)...)
Affinity DataIC50: 37nMAssay Description:In vitro inhibitory concentration evaluated against P21ras Farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM13373(CHEMBL289302 | CHEMBL553980 | (2S)-2-[(2S)-2-[(2S)...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of farnesyl transferase (FTase) of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM13373(CHEMBL289302 | CHEMBL553980 | (2S)-2-[(2S)-2-[(2S)...)
Affinity DataIC50: 25nMAssay Description:Inhibition of bovine FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
LigandPNGBDBM13373(CHEMBL289302 | CHEMBL553980 | (2S)-2-[(2S)-2-[(2S)...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of bovine Farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM13373(CHEMBL289302 | CHEMBL553980 | (2S)-2-[(2S)-2-[(2S)...)
Affinity DataIC50: 57nMAssay Description:In vitro inhibition of bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM13373(CHEMBL289302 | CHEMBL553980 | (2S)-2-[(2S)-2-[(2S)...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM13373(CHEMBL289302 | CHEMBL553980 | (2S)-2-[(2S)-2-[(2S)...)
Affinity DataIC50: 60nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM13373(CHEMBL289302 | CHEMBL553980 | (2S)-2-[(2S)-2-[(2S)...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant FTase using [3H]farnesyldiphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed