BDBM50323213 CHEMBL1208973::cupressuflavone

SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3c(O)cc(O)c4c3oc(cc4=O)-c3ccc(O)cc3)c2o1

InChI Key InChIKey=LADPNODMUXOPRG-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50323213   

TargetCyclin-dependent kinase 5 activator 1(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50323213(cupressuflavone | CHEMBL1208973)
Affinity DataIC50: 9.29E+3nMAssay Description:Inhibition of CDK5/p25 (unknown origin) after 30 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shujitsu University

Curated by ChEMBL
LigandPNGBDBM50323213(cupressuflavone | CHEMBL1208973)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BACE1 after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Catholic University of Daegu

Curated by ChEMBL
LigandPNGBDBM50323213(cupressuflavone | CHEMBL1208973)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Catholic University of Daegu

Curated by ChEMBL
LigandPNGBDBM50323213(cupressuflavone | CHEMBL1208973)
Affinity DataKi:  1.07E+4nMAssay Description:Competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed