BDBM50412087 CUCURBITACIN I::NSC-521777

SMILES CC(C)(O)C=CC(=O)[C@](C)(O)[C@H]1[C@H](O)C[C@@]2(C)[C@@H]3CC=C4[C@@H](CC(=O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@]12C

InChI Key InChIKey=NZZOMHODWAPPJH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412087   

TargetIntegrin alpha-L(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50412087(NSC-521777 | CUCURBITACIN I)
Affinity DataIC50: 950nMAssay Description:Inhibition of LFA1 expressed in human JY cells interaction with ICAM1-IG expressed in human HeLa cell monolayer after 45 mins by cell adhesion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed