BDBM50050431 (-)-calanolide B::(10S,11R,12S)-12-Hydroxy-6,6,10,11-tetramethyl-4-propyl-11,12-dihydro-6H,10H-dipyrano[2,3-f;2',3'-h]chromen-2-one::CHEMBL7187::COSTATOLIDE

SMILES CCCc1cc(=O)oc2c3[C@@H](O)[C@@H](C)[C@H](C)Oc3c3C=CC(C)(C)Oc3c12

InChI Key InChIKey=NIDRYBLTWYFCFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050431   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50050431(CHEMBL7187 | (10S,11R,12S)-12-Hydroxy-6,6,10,11-te...)
Affinity DataIC50: 1.56E+5nMAssay Description:Inhibitory activity against DNA -dependent DNA polymerase (DDDP) of HIV-1 RT Nucleic Acid polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50050431(CHEMBL7187 | (10S,11R,12S)-12-Hydroxy-6,6,10,11-te...)
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibitory activity against RNA-dependent DNA polymerase (RDDP) of HIV-1 RT Nucleic Acid polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed