BDBM50250718 2-alpha-(3'-hydroxy-3'-methylglutaroyl)-24,25-dihydroxylanostan-3-one::CHEMBL452658::Clavaric acid

SMILES C[C@H](CCC(O)C(C)(C)O)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)C[C@@H](OC(=O)CC(C)(O)CC(O)=O)C(=O)C(C)(C)[C@@H]1CC3

InChI Key InChIKey=FNHDSKHVYPYDAZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50250718   

TargetType II restriction enzyme EcoRI(Escherichia coli)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50250718(Clavaric acid | 2-alpha-(3'-hydroxy-3'-methylgluta...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Escherichia coli ECOR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250718(Clavaric acid | 2-alpha-(3'-hydroxy-3'-methylgluta...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human Farnesyltransferase using Ras-CVLSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50250718(Clavaric acid | 2-alpha-(3'-hydroxy-3'-methylgluta...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human Farnesyltransferase using Ras-CVIMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed