BDBM50428068 CHEMBL2322655::Cinnabarinic acid

SMILES Nc1c(C(O)=O)c2nc3c(cccc3oc2cc1=O)C(O)=O

InChI Key InChIKey=FSBKJYLVDRVPTK-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50428068   

TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50428068(Cinnabarinic acid | CHEMBL2322655)
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant N-terminus 6X-histidine-tagged indoleamine 2,3-dioxygenase expressed in Escherichia coli assessed as inhibition of L-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50428068(Cinnabarinic acid | CHEMBL2322655)
Affinity DataIC50: 4.53E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50428068(Cinnabarinic acid | CHEMBL2322655)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50428068(Cinnabarinic acid | CHEMBL2322655)
Affinity DataKi:  326nMAssay Description:Inhibition of human recombinant N-terminus 6X-histidine-tagged indoleamine 2,3-dioxygenase expressed in Escherichia coli assessed as inhibition of L-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed