BDBM50042993 (2E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one::2',4,4',6'-tetrahydroxychalcone::CHEMBL338066::Chalconaringenin

SMILES Oc1ccc(\C=C\C(=O)c2c(O)cc(O)cc2O)cc1

InChI Key InChIKey=YQHMWTPYORBCMF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50042993   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50042993((2E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50042993((2E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl...)
Affinity DataEC50:  4.00E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50042993((2E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article