BDBM50059863 (Z)-2-Methyl-3-tetradecyl-but-2-enedioic acid::CHEMBL103955::chaetomellic acid A

SMILES CCCCCCCCCCCCCC\C(C(O)=O)=C(/C)C(O)=O

InChI Key InChIKey=ULSDRNDLXFVDED-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059863   

LigandPNGBDBM50059863(chaetomellic acid A | (Z)-2-Methyl-3-tetradecyl-bu...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
LigandPNGBDBM50059863(chaetomellic acid A | (Z)-2-Methyl-3-tetradecyl-bu...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
LigandPNGBDBM50059863(chaetomellic acid A | (Z)-2-Methyl-3-tetradecyl-bu...)
Affinity DataIC50: 60nMAssay Description:Activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50059863(chaetomellic acid A | (Z)-2-Methyl-3-tetradecyl-bu...)
Affinity DataIC50: 9.20E+4nMAssay Description:In vitro inhibition of geranylgeranyl-protein transferase type-IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50059863(chaetomellic acid A | (Z)-2-Methyl-3-tetradecyl-bu...)
Affinity DataIC50: 175nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed