BDBM50423643 CEPHARANTHINE

SMILES COc1ccc2C[C@H]3N(C)CCc4cc(OC)c(Oc5c6OCOc6cc6CCN(C)[C@@H](Cc7ccc(Oc1c2)cc7)c56)cc34

InChI Key InChIKey=YVPXVXANRNDGTA-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50423643   

TargetAngiotensin-converting enzyme 2(Human)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50423643(CEPHARANTHINE)
Affinity DataEC50:  350nMAssay Description:Inhibition of ACE2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
LigandPNGBDBM50423643(CEPHARANTHINE)
Affinity DataKi:  1.09E+3nMAssay Description:Displacement of [125I]apamin from human SK3 expressed in HEK293 cells assessed as inhibition constant incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
LigandPNGBDBM50423643(CEPHARANTHINE)
Affinity DataKi:  1.32E+3nMAssay Description:Displacement of [125I]apamin from human SK2 expressed in HEK293 cells assessed as inhibition constant incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Pontificia Universidad Catolica Del Peru

Curated by ChEMBL
LigandPNGBDBM50423643(CEPHARANTHINE)
Affinity DataKi:  7.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Pontificia Universidad Catolica Del Peru

Curated by ChEMBL
LigandPNGBDBM50423643(CEPHARANTHINE)
Affinity DataKi:  5.16E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase-substrate complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed