BDBM50098221 4-Butylamino-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester::CHEMBL8184::Cartazolate::ethyl 4-(butylamino)-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate

SMILES CCCCNc1c(cnc2n(CC)ncc12)C(=O)OCC

InChI Key InChIKey=IQNQAOGGWGCROX-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50098221   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098221(ethyl 4-(butylamino)-1-ethyl-1H-pyrazolo[3,4-b]pyr...)
Affinity DataIC50: 180nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50098221(ethyl 4-(butylamino)-1-ethyl-1H-pyrazolo[3,4-b]pyr...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human PDE4B in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM50098221(ethyl 4-(butylamino)-1-ethyl-1H-pyrazolo[3,4-b]pyr...)
Affinity DataKi:  357nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Warner-Lambert/Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM50098221(ethyl 4-(butylamino)-1-ethyl-1H-pyrazolo[3,4-b]pyr...)
Affinity DataKi:  2.24E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed