BDBM50338981 CHEMBL1685074::calyflorenon B

SMILES CO[C@@H]1C[C@H](OC2=C1C(=O)[C@H](OC)[C@@]1(OC)Oc3c(c(OC)c(OC)c4O[C@@H](C[C@@H](O)c34)c3ccccc3)[C@@]21OC)c1ccccc1

InChI Key InChIKey=XIIREHQYOZVJHT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338981   

LigandPNGBDBM50338981(calyflorenon B | CHEMBL1685074)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of BCRP expressed in MCF-7 MX cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50338981(calyflorenon B | CHEMBL1685074)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of BCRP expressed in MDCK cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50338981(calyflorenon B | CHEMBL1685074)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of MDR1 expressed in MDCK cells using rhodamine 123 staining by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed