BDBM50169808 2-{2-Hydroxy-3-[2-(1H-indol-3-yl)-1,1-dimethyl-ethylamino]-propoxy}-benzamide::2-{2-Hydroxy-3-[2-(1H-indol-3-yl)-1,1-dimethyl-ethylamino]-propoxy}-benzonitrile::BUCINDOLOL::CHEMBL321582

SMILES CC(C)(Cc1c[nH]c2ccccc12)NCC(O)COc1ccccc1C#N

InChI Key InChIKey=FBMYKMYQHCBIGU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169808   

TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169808(CHEMBL321582 | 2-{2-Hydroxy-3-[2-(1H-indol-3-yl)-1...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against recombinant human Cytochrome P450 2D6 (CYP2D6) after incubated for 45 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50169808(CHEMBL321582 | 2-{2-Hydroxy-3-[2-(1H-indol-3-yl)-1...)
Affinity DataIC50: 2.72E+4nMAssay Description:Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed