BDBM50202318 (+)-boldine::(S)-(+)-Boldine::(S)-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol::CHEMBL388342::boldine::cid_10154::cid_248507

SMILES COc1cc-2c(C[C@@H]3N(C)CCc4cc(O)c(OC)c-2c34)cc1O

InChI Key InChIKey=LZJRNLRASBVRRX-UHFFFAOYSA-N

Data  4 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50202318   

TargetMitochondrial peptide methionine sulfoxide reductase(Bovine)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataIC50: 4.78E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetMitochondrial peptide methionine sulfoxide reductase(Bovine)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataIC50: 5.39E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetD(1A) dopamine receptor(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in Wistar rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataIC50: 520nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in Wistar rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Chile

Curated by ChEMBL
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataIC50: 8.10E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha-7 nAChR expressed in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Chile

Curated by ChEMBL
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]cytisine from human alpha-4-beta-2 nAChR expressed in SH-EP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataIC50: 500nMAssay Description:Displacement of [3H]raclopride from rat dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]SCH-23390 from rat dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataIC50: 6.10E+5nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Padua and Institute of Biomolecular Chemistry

Curated by ChEMBL
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataIC50: 700nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]SCH-23390 from rat dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataKi:  370nMAssay Description:Displacement of [3H]raclopride from rat dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Chile

Curated by ChEMBL
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]cytisine from human alpha-4-beta-2 nAChR expressed in SH-EP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Chile

Curated by ChEMBL
LigandPNGBDBM50202318(cid_10154 | cid_248507 | (S)-1,10-dimethoxy-6-meth...)
Affinity DataKi:  6.70E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha-7 nAChR expressed in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed